Description

2-Piperidin-4-Yl-6-Thiophen-2-Yl-Pyridazin-3-One Hydrochloride is a high-purity, non-racemic organic salt with significant potential in advanced pharmaceutical research and development. This compound matters as a sophisticated chemical intermediate, offering a critical building block for medicinal chemists targeting novel therapeutic agents. It is primarily needed by R&D laboratories and pharmaceutical companies engaged in the synthesis of new chemical entities, particularly for central nervous system (CNS) and other biologically active targets. The CAS number for this compound is 1052522-60-7.

Application

This specialized intermediate is designed for high-value research and development applications, including:

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Tool Compound: Employed in vitro to study specific biological pathways and receptor interactions.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in API synthesis.
• Custom Synthesis: A starting material for the contract manufacturing of more complex, target-specific molecules.

Basic Information

Product Name	2-Piperidin-4-Yl-6-Thiophen-2-Yl-Pyridazin-3-One Hydrochloride
CAS No.	1052522-60-7
Molecular Formula	C13H16N3OS • HCl
Molecular Weight	297.81 g/mol (Free base: 262.35 g/mol)
Synonyms	6-(Thiophen-2-yl)-2-(piperidin-4-yl)pyridazin-3(2H)-one hydrochloride; 2-(4-Piperidinyl)-6-(2-thienyl)-3(2H)-pyridazinone hydrochloride; 6-(2-Thienyl)-2-(4-piperidinyl)-3(2H)-pyridazinone HCl; 1052522-60-7; 2-Piperidin-4-yl-6-thiophen-2-yl-2H-pyridazin-3-one hydrochloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research chemicals. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results for assay, purity, and related substances are available upon request, supporting your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.