Description

4-Chloro-2-Methyl-5-Piperazin-1-Yl-2H-Pyridazin-3-One, Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a defined molecular structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially in central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the multi-step synthesis of complex target molecules for preclinical and clinical evaluation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and cGMP production.
• Biochemical Research: May be used as a tool compound to study specific biological pathways or enzyme interactions.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	4-Chloro-2-Methyl-5-Piperazin-1-Yl-2H-Pyridazin-3-One, Hydrochloride
CAS No.	1052270-14-0
Molecular Formula	C9H14Cl2N4O
Molecular Weight	265.14 g/mol
Synonyms	4-Chloro-2-methyl-5-(piperazin-1-yl)pyridazin-3(2H)-one hydrochloride; 5-(Piperazin-1-yl)-4-chloro-2-methyl-2H-pyridazin-3-one hydrochloride; 4-Chloro-2-methyl-5-piperazinyl-3(2H)-pyridazinone hydrochloride; 1052270-14-0; 4-Chloro-2-methyl-5-(1-piperazinyl)-3(2H)-pyridazinone monohydrochloride
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Methyl-5-Piperazin-1-Yl-2H-Pyridazin-3-One, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment. We support development and cGMP-grade requirements, with specifications tailored to your project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.