Description

n-[(1R,2R)-2-Aminocyclohexyl]-N'-[(9R)-6'-Methoxycinchonan-9-Yl]- Thiourea is a sophisticated chiral thiourea derivative, a class of compounds renowned for their utility as organocatalysts and chiral ligands. This high-purity compound is specifically designed for advanced chemical synthesis and research applications where precise stereochemical control is paramount. It is a critical reagent for pharmaceutical R&D, asymmetric catalysis, and the development of novel synthetic methodologies.

Application

• As a highly effective chiral organocatalyst for enantioselective organic transformations, such as Michael additions and acylations.
• As a chiral ligand or co-catalyst in transition metal-catalyzed asymmetric reactions.
• In pharmaceutical research and development for the synthesis of enantiomerically pure drug candidates and intermediates.
• For method development in academic and industrial laboratories focused on asymmetric synthesis.
• As a key building block in the preparation of more complex chiral molecules and catalysts.
• In fine chemical synthesis where high enantiomeric excess (ee) and yield are required.

Basic Information

Product Name	n-[(1R,2R)-2-Aminocyclohexyl]-N'-[(9R)-6'-Methoxycinchonan-9-Yl]- Thiourea
CAS No.	1052187-54-8
Molecular Formula	C26H34N4O2S
Molecular Weight	466.64 g/mol
Synonyms	(1R,2R)-N-[(9R)-6'-Methoxycinchonan-9-yl]-N'-(2-aminocyclohexyl)thiourea; (1R,2R)-2-Amino-N-[(9R)-6'-methoxycinchonan-9-yl]-N'-cyclohexylthiourea; Cinchona Alkaloid-Derived Thiourea Catalyst; Chiral Thiourea Organocatalyst; (R,R)-DACH-Thiourea-Cinchona Hybrid; (1R,2R)-DACH-Cinchona Thiourea; Asymmetric Thiourea Catalyst; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our n-[(1R,2R)-2-Aminocyclohexyl]-N'-[(9R)-6'-Methoxycinchonan-9-Yl]- Thiourea is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity. Each lot is characterized and tested using advanced analytical techniques, including HPLC, NMR, and chiral analysis, to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.