Description

n-[(1R,2R)-2-Aminocyclohexyl]-N'-(9R)-Cinchonan-9-Yl-Thiourea CAS NO 1052184-40-3 is a sophisticated chiral thiourea derivative, a class of compounds renowned for their utility as organocatalysts and ligands in asymmetric synthesis. Its value lies in enabling highly selective chemical transformations, which are critical for producing enantiomerically pure intermediates in pharmaceutical and fine chemical research. This product is essential for R&D chemists and process development scientists working on the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials where stereochemical control is paramount.

Application

• As a highly selective organocatalyst for enantioselective reactions, such as Michael additions and aldol condensations.
• As a chiral ligand in metal-catalyzed asymmetric synthesis for constructing complex molecular architectures.
• In pharmaceutical research and development for the synthesis of enantiomerically pure drug candidates and intermediates.
• In academic research focused on developing new catalytic methodologies and studying reaction mechanisms.
• For the fine chemical industry in the production of specialty chemicals requiring precise stereochemistry.
• As a key building block or reagent in the synthesis of complex natural products and their analogs.

Basic Information

Product Name	n-[(1R,2R)-2-Aminocyclohexyl]-N'-(9R)-Cinchonan-9-Yl-Thiourea
CAS No.	1052184-40-3
Molecular Formula	C₂₅H₃₂N₄OS
Molecular Weight	428.61 g/mol
Synonyms	(1R,2R)-N-[(9R)-Cinchonan-9-yl]-N'-(2-aminocyclohexyl)thiourea; (1R,2R)-2-Amino-N-[(9R)-cinchonan-9-yl]-N'-cyclohexylthiourea; Cinchona Alkaloid-Derived Thiourea Organocatalyst; (R,R)-DACH-Thiourea-Cinchona Hybrid Catalyst; Chiral Thiourea Catalyst; Asymmetric Organocatalyst; 1052184-40-3; Cinchonidine-derived thiourea
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all relevant specifications are available upon request. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.