Description

3-Bromotetrahydro-2H-Pyran-2-Carbonitrile is a versatile and high-value brominated heterocyclic building block. This compound is essential for advanced organic synthesis, particularly in constructing complex molecular architectures for pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially those containing functionalized tetrahydropyran rings.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functional polymers and advanced organic materials with specific electronic or structural properties.
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination.
• Chemical Biology Probes: Useful for synthesizing molecular probes to study biological pathways and enzyme functions.

Basic Information

Product Name	3-Bromotetrahydro-2H-Pyran-2-Carbonitrile
CAS No.	1051940-71-6
Molecular Formula	C6H8BrNO
Molecular Weight	190.04 g/mol
Synonyms	3-Bromotetrahydro-2H-pyran-2-carbonitrile; 2H-Pyran-2-carbonitrile, 3-bromotetrahydro-; 3-Bromotetrahydropyran-2-carbonitrile; 3-Bromo-3,4,5,6-tetrahydro-2H-pyran-2-carbonitrile; 3-Bromotetrahydro-2-pyrancarbonitrile; Tetrahydro-3-bromo-2H-pyran-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 3-Bromotetrahydro-2H-Pyran-2-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.