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n-Carbobenzoxy-1,12-Diaminododecane Hydrochloride CAS NO 1051420-16-6


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CAS No.:1051420-16-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-Carbobenzoxy-1,12-Diaminododecane Hydrochloride is a protected diamine derivative, specifically the hydrochloride salt of a Cbz-protected long-chain aliphatic diamine. This compound serves as a crucial building block in organic synthesis and peptide chemistry, where it provides a protected primary amine functionality for controlled chain elongation. It is primarily needed by researchers and manufacturers in the pharmaceutical and bioconjugation sectors for developing novel therapeutic agents, peptide-based drugs, and specialized polymers.

Application

  • Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in peptide and polyamine-based therapeutics.
  • Peptide Synthesis: Used as a protected diamine monomer in solid-phase and solution-phase peptide synthesis to introduce specific spacer or linker units.
  • Bioconjugation Reagent: Facilitates the controlled attachment of biomolecules (e.g., proteins, antibodies) to surfaces, polymers, or other molecules for diagnostic and therapeutic applications.
  • Polymer Chemistry: Serves as a monomer or chain extender in the production of specialized polyamides, polyurethanes, and other functional polymers.
  • Cross-linking Agent: Utilized in material science to create cross-linked networks for hydrogels, resins, and coatings with tailored properties.
  • Research & Development: Essential tool in academic and industrial R&D for exploring new chemical entities and biochemical pathways.

Basic Information

Product Name n-Carbobenzoxy-1,12-Diaminododecane Hydrochloride
CAS No. 1051420-16-6
Molecular Formula C20H35ClN2O2
Molecular Weight 371.0 g/mol (approx.)
Synonyms Nα-Cbz-1,12-diaminododecane hydrochloride; N-Carbobenzyloxy-1,12-diaminododecane hydrochloride; 1,12-Diaminododecane, N1-(phenylmethoxy)carbonyl-, hydrochloride (1:1); Cbz-DAD·HCl; Z-1,12-Diaminododecane hydrochloride; Benzyl (12-amino-1-aminododecyl)carbamate hydrochloride; (12-Amino-1-aminododecyl)carbamic acid benzyl ester hydrochloride
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Quality Control

Our n-Carbobenzoxy-1,12-Diaminododecane Hydrochloride is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), impurity profile, and physical characteristics are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Heavy Metals ≤ 20 ppm
Residue on Ignition ≤ 0.1%
Solubility Soluble in DMF, DMSO; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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