Description

3-(2-Bromoethyl)Tetrahydro-2H-Pyran is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a reactive bromoethyl side chain tethered to a tetrahydropyran ring, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection agent development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in creating spirocyclic or bridged heterocyclic systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific ether-linked alkyl halide functionalities.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of functionalized polymers and dendrimers with tailored properties.
• Cross-Coupling Reactions: Acts as an alkyl halide component in various palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura or Negishi couplings.
• Nucleophilic Substitution Scaffold: The bromoethyl group provides an excellent handle for further functionalization via nucleophilic substitution, enabling chain elongation and introduction of diverse functional groups.

Basic Information

Product Name	3-(2-Bromoethyl)Tetrahydro-2H-Pyran
CAS No.	1050496-64-4
Molecular Formula	C7H13BrO
Molecular Weight	193.08 g/mol
Synonyms	2-(2-Bromoethyl)tetrahydro-2H-pyran; Tetrahydro-2H-pyran-3-ylmethyl bromide; 3-(Bromoethyl)tetrahydropyran; 2-(Bromoethyl)tetrahydropyran; 3-(2-Bromoethyl)oxane; Bromoethyltetrahydropyran; 1050496-64-4; 3-(2-Bromoethyl)tetrahydropyran
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Bromoethyl)Tetrahydro-2H-Pyran is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and process chemistry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by GC/HPLC and NMR is supplied with each shipment, ensuring full traceability and compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.