Description

4-(Bromomethyl)Tetrahydro-2,2-Dimethyl-2H-Pyran is a versatile brominated heterocyclic building block, prized for its reactive bromomethyl functionality. This compound is essential for introducing the tetrahydro-2,2-dimethyl-2H-pyranyl moiety into target molecules, enabling the synthesis of complex intermediates. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting novel therapeutic agents.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents, herbicides, and fungicides, leveraging its structural motif for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Employed in the synthesis of functional monomers or additives for polymers and advanced materials with tailored properties.
• Chemical Biology Probes: Useful for the synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Item	Details
Product Name	4-(Bromomethyl)Tetrahydro-2,2-Dimethyl-2H-Pyran
CAS No.	1050494-70-6
Molecular Formula	C8H15BrO
Molecular Weight	207.11 g/mol
Synonyms	4-(Bromomethyl)-2,2-dimethyltetrahydro-2H-pyran; 2,2-Dimethyltetrahydro-2H-pyran-4-ylmethyl bromide; 4-(Bromomethyl)-2,2-dimethyloxane; THP-Bromomethyl derivative; Bromomethyl-THP; 2,2-Dimethyl-4-bromomethyltetrahydropyran; 4-Bromomethyl-2,2-dimethyltetrahydropyran
EINECS	Contact for details

Quality Control

Every batch of 4-(Bromomethyl)Tetrahydro-2,2-Dimethyl-2H-Pyran is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.