Description

Ethanone, 1-[(4R,5R)-5-Ethenyl-2,2-Dimethyl-1,3-Dioxolan-4-Yl]- is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound matters for its role in the stereoselective synthesis of complex bioactive molecules, offering a critical handle for constructing specific three-dimensional architectures. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing new active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in antiviral, anti-inflammatory, or central nervous system (CNS) therapeutic areas.
• Asymmetric Synthesis: Used as a precursor in catalytic asymmetric reactions to introduce specific stereocenters with high enantiomeric purity.
• Natural Product Synthesis: Serves as a building block for the total synthesis of complex natural products with biological activity.
• Fragrance & Flavor Chemistry: Potential intermediate for creating specific chiral odorants or flavor compounds where stereochemistry influences the sensory profile.
• Agrochemical Research: Employed in the development of new, stereochemically defined active ingredients for crop protection.
• Material Science: Can be utilized as a monomer or cross-linking agent in the development of specialized polymers with tailored properties.

Basic Information

Product Name	Ethanone, 1-[(4R,5R)-5-Ethenyl-2,2-Dimethyl-1,3-Dioxolan-4-Yl]-
CAS No.	1042237-51-3
Molecular Formula	C9H14O3
Molecular Weight	170.21 g/mol
Synonyms	1-[(4R,5R)-5-Ethenyl-2,2-dimethyl-1,3-dioxolan-4-yl]ethanone; (4R,5R)-4-Acetyl-5-vinyl-2,2-dimethyl-1,3-dioxolane; (4R-cis)-4-Acetyl-2,2-dimethyl-5-vinyl-1,3-dioxolane; Chiral Dioxolane Acetone Derivative; (R,R)-Dioxolane Acetyl Vinyl Compound
EINECS	Contact for details

Quality Control

Our Ethanone, 1-[(4R,5R)-5-Ethenyl-2,2-Dimethyl-1,3-Dioxolan-4-Yl]- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with full specification data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.