Description

Potassium trans-2-Methylcyclohexyltrifluoroborate is a high-purity organotrifluoroborate salt, a valuable class of reagents prized for their stability and versatility in advanced synthetic chemistry. This compound serves as a crucial building block for the efficient introduction of the trans-2-methylcyclohexyl moiety into complex molecular architectures via cross-coupling reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A stable, air- and moisture-tolerant alternative to boronic acids for palladium-catalyzed C-C bond formation.
• Pharmaceutical Intermediate Synthesis: Key reagent for constructing chiral, sterically hindered cyclohexyl scaffolds present in drug candidates.
• Agrochemical Product Development: Used in the synthesis of novel herbicides, fungicides, and insecticides requiring specific stereochemistry.
• Ligand and Catalyst Preparation: Building block for creating specialized phosphine or N-heterocyclic carbene ligands with cyclohexyl groups.
• Materials Science Research: Incorporation into organic semiconductors, liquid crystals, or polymers to modify physical properties.
• Process Chemistry & Scale-up: Favored in manufacturing due to its improved handling characteristics and shelf-life compared to sensitive boronic acids.

Basic Information

Product Name	Potassium trans-2-Methylcyclohexyltrifluoroborate
CAS No.	1041642-14-1
Molecular Formula	C7H13BF3K
Molecular Weight	204.09 g/mol
Synonyms	trans-2-Methylcyclohexyltrifluoroborate Potassium Salt; Potassium (trans-2-Methylcyclohexyl)trifluoroborate; trans-2-Methylcyclohexanetrifluoroborate Potassium Salt; (1R,2S)-2-Methylcyclohexyltrifluoroborate Potassium Salt; (1S,2R)-2-Methylcyclohexyltrifluoroborate Potassium Salt; Potassium trans-2-Methylcyclohexyl-BF3; Organotrifluoroborate Salt KB-0543 (Research Code)
EINECS	Contact for details

Quality Control

Every batch of our Potassium trans-2-Methylcyclohexyltrifluoroborate is manufactured and analyzed under strict quality management protocols to ensure consistency and reliability for your critical synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by NMR), isomeric composition, and moisture content. Our quality systems are designed to support cGMP development and production for the pharmaceutical industry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) to prevent decomposition and maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (¹H/¹¹B/¹⁹F NMR)	≥95.0%
Isomeric Purity (trans- isomer)	≥98.0%
Water Content (KF)	≤2.0%
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.