Description

4-(2-Methoxyphenyl)Tetrahydro-2H-Pyran-4-Carboxylic Acid is a versatile and synthetically valuable organic building block characterized by its unique fused ring structure containing both a methoxyphenyl group and a carboxylic acid functionality. This compound is of significant interest for its role as a key intermediate in the development of complex molecules, particularly within the pharmaceutical and agrochemical sectors. It is primarily sought after by research chemists and process development scientists engaged in medicinal chemistry, custom synthesis, and the production of advanced fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, leveraging its complex heterocyclic core.
• Ligand and Catalyst Development: The carboxylic acid and ether groups make it a useful starting material for creating chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for the synthesis of specialized polymers with tailored thermal or optical properties.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for method development and exploratory chemistry projects.
• Custom Synthesis and Scal-up: Provided as a high-purity intermediate for custom manufacturing projects from gram to multi-kilogram scale.

Basic Information

Item	Details
Product Name	4-(2-Methoxyphenyl)Tetrahydro-2H-Pyran-4-Carboxylic Acid
CAS No.	1039931-72-0
Molecular Formula	C14H18O4
Molecular Weight	250.29 g/mol
Synonyms	4-(2-Methoxyphenyl)tetrahydro-2H-pyran-4-carboxylic acid; 4-(o-Methoxyphenyl)tetrahydro-2H-pyran-4-carboxylic acid; 2H-Pyran-4-carboxylic acid, 4-(2-methoxyphenyl)tetrahydro-; 4-Carboxy-4-(2-methoxyphenyl)tetrahydropyran; Tetrahydro-4-(2-methoxyphenyl)-2H-pyran-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 4-(2-Methoxyphenyl)Tetrahydro-2H-Pyran-4-Carboxylic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, NMR, and MS for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. Our quality management system supports compliance with cGMP and ISO standards for research and commercial-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its carboxylic acid nature, keep away from strong bases, oxidizing agents, and sources of ignition. For long-term storage, consider inert atmosphere packaging to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.