Description

(1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Pyrazol-4-Yl)Methanol is a high-value heterocyclic building block featuring a fused pyrazole and tetrahydropyran structure. This compound is essential for medicinal chemistry research and pharmaceutical development, serving as a versatile intermediate for constructing complex bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral research programs.
• Medicinal Chemistry Scaffold: Used in hit-to-lead and lead optimization stages to explore structure-activity relationships (SAR) due to its privileged heterocyclic core.
• Agrochemical Synthesis: Building block for creating novel fungicides, herbicides, and plant growth regulators.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Ligand Development: Serves as a precursor for chelating ligands in catalysis and material science applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or non-GMP conditions.

Basic Information

Product Name	(1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Pyrazol-4-Yl)Methanol
CAS No.	1038392-13-0
Molecular Formula	C9H14N2O2
Molecular Weight	182.22 g/mol
Synonyms	1-(Oxan-2-yl)-1H-pyrazol-4-ylmethanol; 4-(Hydroxymethyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole; 1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazole-4-methanol; (1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazol-4-yl)methanol; THP-Protected Pyrazolylmethanol; 1-THP-1H-pyrazol-4-ylmethanol
EINECS	Contact for details

Quality Control

Our (1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Pyrazol-4-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all specification results. We support development and commercial projects with material suitable for research use, pilot plant, and cGMP manufacturing scales.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.