Description

3,4-Bis[(tert-Butyldimethylsilyl)Oxy]Benzyl Alcohol is a high-purity, protected benzyl alcohol derivative featuring two tert-butyldimethylsilyl (TBDMS) ether groups. This compound is a critical advanced pharmaceutical intermediate and a versatile synthetic building block in organic chemistry, prized for its role in constructing complex molecular architectures. It is essential for researchers and manufacturers in pharmaceutical development, fine chemical synthesis, and academic research who require reliable, high-quality intermediates for multi-step synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those targeting neurological and cardiovascular diseases.
• Organic Synthesis Building Block: Used in multi-step synthesis for the controlled introduction of protected dihydroxybenzyl motifs.
• Protecting Group Chemistry: The TBDMS-protected hydroxyl groups provide stability during synthetic transformations, allowing for selective deprotection later.
• Research & Development: Serves as a standard reagent in medicinal chemistry labs for exploring new chemical entities and structure-activity relationships.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, agrochemicals, and high-value performance materials.
• Academic Research: Used in university and institutional labs for methodology development and training in advanced synthetic techniques.

Basic Information

Product Name	3,4-Bis[(tert-Butyldimethylsilyl)Oxy]Benzyl Alcohol
CAS No.	1036243-79-4
Molecular Formula	C19H36O3Si2
Molecular Weight	368.67 g/mol
Synonyms	3,4-Bis-O-(tert-butyldimethylsilyl)benzyl alcohol; 3,4-Bis[(tert-butyldimethylsiloxy)]benzyl alcohol; 3,4-Di-O-TBDMS-benzyl alcohol; (3,4-Bis((tert-butyldimethylsilyl)oxy)phenyl)methanol; Benzyl alcohol, 3,4-bis[(1,1-dimethylethyl)dimethylsilyl]oxy]-; TBDMS-protected 3,4-dihydroxybenzyl alcohol
EINECS	Contact for details

Quality Control

Our 3,4-Bis[(tert-Butyldimethylsilyl)Oxy]Benzyl Alcohol is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our commitment to cGMP and ISO standards ensures a reliable supply of this high-value intermediate for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.