Description

4-Bromo-1-Ethyl-2-Iodobenzene is a high-purity, multi-halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both bromine and iodine substituents on an ethylbenzene core, makes it a versatile and valuable precursor for cross-coupling reactions, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily utilized by research chemists and process development scientists for constructing complex molecules, including active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, especially those requiring complex aryl-aryl or aryl-heteroaryl linkages via Suzuki, Stille, or other palladium-catalyzed cross-coupling reactions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the introduction of specific halogenated aromatic motifs is required for biological activity.
• Material Science: Acts as a monomer or precursor for the creation of specialty polymers, liquid crystals, and organic electronic materials that benefit from its distinct halogenated structure.
• Chemical Synthesis: Functions as a versatile reagent in organic chemistry for sequential functionalization, enabling the selective introduction of other functional groups at the bromine or iodine sites.
• Ligand and Catalyst Development: Employed in the preparation of specialized phosphine or N-heterocyclic carbene (NHC) ligands used in homogeneous catalysis.

Basic Information

Product Name	4-Bromo-1-Ethyl-2-Iodobenzene
CAS No.	1033760-94-9
Molecular Formula	C8H8BrI
Molecular Weight	310.96 g/mol
Synonyms	1-Bromo-4-ethyl-2-iodobenzene; 2-Iodo-4-bromoethylbenzene; 4-Ethyl-1-bromo-2-iodobenzene; 4-Bromo-2-iodoethylbenzene; (4-Bromo-2-iodophenyl)ethane; Ethyl-4-bromo-2-iodobenzene
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-Ethyl-2-Iodobenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including GC, HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC / GC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.