Description

(4S,5S)-1,3-Bis(2-(Methoxymethyl)Phenyl)-4,5-Diphenyl-4,5-Dihydro-1H-Imidazol-3-Ium Tetrafluoroborate is a high-value, chiral imidazolinium salt that serves as a key precursor or catalyst in advanced asymmetric synthesis. Its importance lies in its well-defined stereochemistry and ionic nature, which are critical for inducing high enantioselectivity in organic transformations. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing novel active pharmaceutical ingredients (APIs) and specialty materials.

Application

• Asymmetric Organocatalysis: Employed as a chiral phase-transfer catalyst or catalyst precursor for enantioselective alkylation, Michael addition, and other C-C bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: A critical building block in the multi-step synthesis of complex, chiral drug molecules, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Ligand for Transition Metal Complexes: Used to synthesize chiral N-heterocyclic carbene (NHC) ligands for asymmetric metal-catalyzed processes like hydrogenation and cross-coupling.
• Material Science Research: Investigated for the development of chiral ionic liquids or as a structural component in advanced organic frameworks.
• Process Chemistry Development: Utilized in scaling up and optimizing synthetic routes for commercial production of high-value enantiopure compounds.
• Academic & Industrial R&D: Serves as a standard or reagent in method development for new catalytic asymmetric reactions.

Basic Information

Product Name	(4S,5S)-1,3-Bis(2-(Methoxymethyl)Phenyl)-4,5-Diphenyl-4,5-Dihydro-1H-Imidazol-3-Ium Tetrafluoroborate
CAS No.	1033618-53-9
Molecular Formula	C32H33BF4N2O2
Molecular Weight	564.43 g/mol
Synonyms	(4S,5S)-1,3-Bis[2-(methoxymethyl)phenyl]-4,5-diphenyl-4,5-dihydro-1H-imidazol-3-ium tetrafluoroborate; (S,S)-1,3-Bis(2-methoxymethylphenyl)-4,5-diphenylimidazolinium Tetrafluoroborate; (S,S)-Imidazolinium Salt PTC Catalyst; Chiral Imidazolinium Tetrafluoroborate; (4S,5S)-4,5-Dihydro-1,3-bis[2-(methoxymethyl)phenyl]-4,5-diphenyl-1H-imidazol-3-ium tetrafluoroborate(1-); Asymmetric Phase Transfer Catalyst Precursor
EINECS	Contact for details

Quality Control

Our (4S,5S)-1,3-Bis(2-(Methoxymethyl)Phenyl)-4,5-Diphenyl-4,5-Dihydro-1H-Imidazol-3-Ium Tetrafluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for sensitive catalytic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of pharmaceutical R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) when opening the container for use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.