Description

(4S,5S)-1,3-Bis(2-Isopropoxyphenyl)-4,5-Diphenyl-4,5-Dihydro-1H-Imidazol-3-Ium Tetrafluoroborate is a chiral imidazolium salt that serves as a highly effective and selective organocatalyst. Its value lies in enabling asymmetric synthesis with excellent enantioselectivity and yield under mild reaction conditions. This compound is essential for researchers and process chemists in the pharmaceutical and fine chemical industries developing novel active ingredients and advanced intermediates.

Application

• Asymmetric Organocatalysis: A key catalyst for enantioselective transformations such as Diels-Alder, Michael, and Mannich reactions.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of chiral drug candidates, particularly for central nervous system and cardiovascular targets.
• Fine Chemical Production: Facilitates the synthesis of complex, high-value chiral molecules for agrochemicals and specialty materials.
• Methodology Development: A valuable tool for academic and industrial research groups exploring new catalytic asymmetric pathways.
• Ligand Precursor: Can be utilized in the preparation of chiral N-heterocyclic carbene (NHC) ligands for transition metal catalysis.

Basic Information

Product Name	(4S,5S)-1,3-Bis(2-Isopropoxyphenyl)-4,5-Diphenyl-4,5-Dihydro-1H-Imidazol-3-Ium Tetrafluoroborate
CAS No.	1033618-51-7
Molecular Formula	C32H33BF4N2O2
Molecular Weight	564.43 g/mol
Synonyms	(4S,5S)-1,3-Bis(2-isopropoxyphenyl)-4,5-diphenyl-4,5-dihydro-1H-imidazol-3-ium tetrafluoroborate; (S,S)-1,3-Bis(2-isopropoxyphenyl)-4,5-diphenyl-4,5-dihydro-1H-imidazolium Tetrafluoroborate; (S,S)-Imidazolium Salt Organocatalyst; Chiral Imidazolium BF4 Salt; (4S,5S)-2,2'-Isopropoxybenzhydryl-4,5-diphenylimidazolidinium Tetrafluoroborate; MacMillan Catalyst Derivative; Asymmetric Imidazolidinium Catalyst
EINECS	Contact for details

Quality Control

Every batch of our (4S,5S)-1,3-Bis(2-Isopropoxyphenyl)-4,5-Diphenyl-4,5-Dihydro-1H-Imidazol-3-Ium Tetrafluoroborate is manufactured under strict quality management systems. We ensure high chiral purity and chemical integrity through comprehensive analytical techniques including HPLC, NMR, and specific rotation measurement. Certificates of Analysis (COA) with full specification data are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to maintain stability and catalytic activity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.