Description

(4S,5S)-1,3-Bis(2,6-Diethylphenyl)-4,5-Diphenyl-4,5-Dihydro-1H-Imidazol-3-Ium Tetrafluoroborate is a high-value, chiral imidazolium salt primarily utilized as a sophisticated organocatalyst or chiral ligand in asymmetric synthesis. Its precise stereochemistry and robust ionic structure make it a critical component for achieving high enantioselectivity in complex organic transformations. This compound is essential for research and development laboratories in the pharmaceutical and fine chemical industries, where it enables the production of enantiomerically pure intermediates and active pharmaceutical ingredients (APIs).

Application

• Asymmetric Organocatalysis: Employed as a chiral phase-transfer catalyst (PTC) for alkylation, Michael addition, and other enantioselective C-C bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: Key catalyst in the R&D and scale-up synthesis of chiral drug molecules, particularly for central nervous system (CNS) and cardiovascular targets.
• Fine Chemical Production: Used in the manufacture of high-value specialty chemicals, flavors, and fragrances requiring precise stereochemical control.
• Academic & Industrial Research: A valuable tool for methodology development in synthetic organic chemistry within university and corporate R&D settings.
• Ligand for Metal Complexes: Can serve as a precursor or auxiliary ligand in the formation of chiral metal complexes for catalysis.
• Process Chemistry Optimization: Applied to improve the yield and enantiomeric excess (ee) in established synthetic routes for commercial production.

Basic Information

Product Name	(4S,5S)-1,3-Bis(2,6-Diethylphenyl)-4,5-Diphenyl-4,5-Dihydro-1H-Imidazol-3-Ium Tetrafluoroborate
CAS No.	1033618-45-9
Molecular Formula	C37H41BF4N2
Molecular Weight	600.55 g/mol
Synonyms	(4S,5S)-1,3-Bis(2,6-diethylphenyl)-4,5-diphenyl-4,5-dihydro-1H-imidazol-3-ium tetrafluoroborate; (S,S)-1,3-Bis(2,6-diethylphenyl)-4,5-diphenylimidazolinium tetrafluoroborate; Chiral Imidazolinium Tetrafluoroborate Salt; (S,S)-Imidazolinium PTC; Asymmetric Phase-Transfer Catalyst; (4S,5S)-4,5-Dihydro-4,5-diphenyl-1,3-bis(2,6-diethylphenyl)-1H-imidazol-3-ium tetrafluoroborate; 1033618-45-9
EINECS	Contact for details

Quality Control

Our production of (4S,5S)-1,3-Bis(2,6-Diethylphenyl)-4,5-Diphenyl-4,5-Dihydro-1H-Imidazol-3-Ium Tetrafluoroborate adheres to stringent internal quality standards to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.