Description

(4S,5S)-1,3-Bis(2,6-Dimethylphenyl)-4,5-Diphenyl-4,5-Dihydro-1H-Imidazol-3-Ium Tetrafluoroborate is a high-value, chiral imidazolinium salt that serves as a critical precursor or ligand for advanced asymmetric organocatalysis. This compound matters for its ability to facilitate highly enantioselective transformations, which are essential for producing single-isomer active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors who require precise stereochemical control in their synthetic processes.

Application

• Asymmetric Organocatalysis: As a key chiral catalyst or catalyst precursor for enantioselective C-C and C-X bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: For the stereoselective production of chiral drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: In the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Methodology Development: Used by academic and industrial R&D labs to develop new catalytic asymmetric synthetic protocols.
• Fine Chemical Manufacturing: For the commercial-scale production of high-value, optically pure specialty chemicals and flavors/fragrances.
• Ligand for Metal Complexes: As a chiral N-heterocyclic carbene (NHC) precursor for forming transition metal complexes used in cross-coupling and other metal-catalyzed reactions.

Basic Information

Product Name	(4S,5S)-1,3-Bis(2,6-Dimethylphenyl)-4,5-Diphenyl-4,5-Dihydro-1H-Imidazol-3-Ium Tetrafluoroborate
CAS No.	1033618-43-7
Molecular Formula	C31H31N2•BF4
Molecular Weight	518.40 g/mol
Synonyms	(4S,5S)-1,3-Bis(2,6-dimethylphenyl)-4,5-diphenyl-4,5-dihydro-1H-imidazol-3-ium tetrafluoroborate; (S,S)-1,3-Bis(2,6-dimethylphenyl)-4,5-diphenylimidazolinium Tetrafluoroborate; (S,S)-Imidazolinium Salt; Chiral Imidazolinium Tetrafluoroborate; NHC Precursor Salt; Asymmetric Organocatalyst Precursor; (4S,5S)-2,3-Dihydro-1,3-bis(2,6-dimethylphenyl)-4,5-diphenyl-1H-imidazol-3-ium tetrafluoroborate
EINECS	Contact for details

Quality Control

Every batch of our (4S,5S)-1,3-Bis(2,6-Dimethylphenyl)-4,5-Diphenyl-4,5-Dihydro-1H-Imidazol-3-Ium Tetrafluoroborate undergoes rigorous analytical testing to ensure high chemical purity and enantiomeric excess (ee) suitable for demanding catalytic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, chiral purity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of pharmaceutical R&D and cGMP-compliant fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain stability and catalytic activity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (ee) (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.