Description

3-Bromo-n-(tert-Butyl)-5-Methylbenzenesulfonamide is a high-purity, functionalized benzenesulfonamide derivative designed for advanced chemical synthesis. This compound serves as a critical synthetic intermediate and pharmacophore building block in the development of novel active molecules. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a sterically hindered sulfonamide moiety into their target structures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, particularly those targeting enzymes where the sulfonamide group acts as a zinc-binding motif.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its halogenated aromatic structure for bioactivity.
• Chemical Biology Probes: Serves as a precursor for creating molecular probes to study protein function and enzyme inhibition.
• Material Science: Potential monomer or additive in the synthesis of specialized polymers with unique thermal or chemical resistance properties.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactive bromine substituent.
• Ligand Development: The tert-butyl sulfonamide group can be utilized in the design of novel ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	3-Bromo-n-(tert-Butyl)-5-Methylbenzenesulfonamide
CAS No.	1033201-97-6
Molecular Formula	C11H16BrNO2S
Molecular Weight	306.22 g/mol
Synonyms	3-Bromo-N-tert-butyl-5-methylbenzenesulfonamide; 5-Methyl-3-bromo-N-(tert-butyl)benzenesulfonamide; Benzenesulfonamide, 3-bromo-N-(1,1-dimethylethyl)-5-methyl-; N-(tert-Butyl)-3-bromo-5-methylbenzenesulfonamide; 3-Bromo-5-methyl-N-(tert-butyl)benzenesulfonamide; 3-Bromo-N-(tert-butyl)-5-methylbenzene-1-sulfonamide; 1033201-97-6
EINECS	Contact for details

Quality Control

Our 3-Bromo-n-(tert-Butyl)-5-Methylbenzenesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.