Description

3-Pyridazinecarbonitrile, 6-[[1-[[3-Fluoro-5-(Trifluoromethyl)Phenyl]Methyl]-4-Piperidinyl]Amino]- is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• API Development: Incorporated into the synthesis of potential Active Pharmaceutical Ingredients (APIs), especially for neurological and oncological targets.
• Biochemical Tool Compound: May be utilized in vitro as a probe to study enzyme inhibition or receptor binding mechanisms.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis for clients.

Basic Information

Product Name	3-Pyridazinecarbonitrile, 6-[[1-[[3-Fluoro-5-(Trifluoromethyl)Phenyl]Methyl]-4-Piperidinyl]Amino]-
CAS No.	1032714-06-9
Molecular Formula	C18H15F4N5
Molecular Weight	377.34 g/mol
Synonyms	6-[[1-[[3-Fluoro-5-(trifluoromethyl)phenyl]methyl]-4-piperidinyl]amino]-3-pyridazinecarbonitrile; 6-((1-((3-Fluoro-5-(trifluoromethyl)benzyl)piperidin-4-yl)amino)pyridazine-3-carbonitrile; 1032714-06-9; UNII-9Q6JZ6V8FQ; 9Q6JZ6V8FQ; 6-[(1-{[3-Fluoro-5-(trifluoromethyl)phenyl]methyl}piperidin-4-yl)amino]pyridazine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is subjected to rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and cGMP-grade requirements, with quality protocols designed to meet the stringent standards of the pharmaceutical industry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed in a dry environment to prevent moisture uptake. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.