Description

6-Chloro-3-Thiophen-2-Yl-[1,2,4]Triazolo[4,3-B]Pyridazine is a high-value heterocyclic organic compound featuring a fused triazolopyridazine core substituted with a chloro group and a thiophene ring. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D teams in the pharmaceutical, agrochemical, and material science sectors for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Medicinal Chemistry Research: Serves as a privileged scaffold for structure-activity relationship (SAR) studies and high-throughput screening libraries.
• Agrochemical Development: Used in the research and development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic structure.
• Organic Electronic Materials: Investigated as a building block for organic semiconductors and light-emitting materials, leveraging the electron-rich thiophene moiety.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.

Basic Information

Product Name	6-Chloro-3-Thiophen-2-Yl-[1,2,4]Triazolo[4,3-B]Pyridazine
CAS No.	1032705-56-8
Molecular Formula	C9H5ClN4S
Molecular Weight	236.68 g/mol
Synonyms	6-Chloro-3-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazine; 6-Chloro-3-(2-thienyl)-[1,2,4]triazolo[4,3-b]pyridazine; 1032705-56-8; 6-Chloro-3-thiophen-2-yl-[1,2,4]triazolo[4,3-b]pyridazine; 6-Chloro-3-(2-thienyl)-s-triazolo[4,3-b]pyridazine; 3-(Thiophen-2-yl)-6-chloro-[1,2,4]triazolo[4,3-b]pyridazine
EINECS	Contact for details

Quality Control

Our production of 6-Chloro-3-Thiophen-2-Yl-[1,2,4]Triazolo[4,3-B]Pyridazine adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to support cGMP compliance for pharmaceutical applications, and we can accommodate custom purity specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.