Description

7-Trimethylstannylisoquinoline is a specialized organotin compound used as a key building block in advanced organic synthesis. Its value lies in its ability to act as a versatile coupling partner in cross-coupling reactions, such as the Stille reaction, enabling the efficient construction of complex heterocyclic architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, as well as in materials science for creating novel organic electronic materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those containing the isoquinoline scaffold for potential therapeutic applications.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the organotin moiety facilitates the introduction of complex functional groups.
• Materials Science: Employed in the synthesis of organic semiconductors, light-emitting diodes (OLEDs), and other advanced electronic materials due to its ability to form carbon-carbon bonds under mild conditions.
• Catalyst & Ligand Development: Acts as a starting material for creating novel organotin catalysts or ligands used in homogeneous catalysis.
• Chemical Synthesis: A versatile reagent for palladium-catalyzed cross-coupling reactions (Stille coupling) to form biaryl and heterobiaryl compounds.
• Academic & R&D: A valuable tool for synthetic organic chemists in universities and corporate R&D labs exploring new reaction methodologies and complex molecule construction.

Basic Information

Product Name	7-Trimethylstannylisoquinoline
CAS No.	1032315-16-4
Molecular Formula	C₁₂H₁₅NSn
Molecular Weight	276.95 g/mol
Synonyms	Isoquinoline, 7-(trimethylstannyl)-; 7-(Trimethylstannyl)isoquinoline; Trimethyl(7-isoquinolyl)stannane; Stannane, trimethyl(7-isoquinolyl)-; 7-Trimethyltin-isoquinoline; 7-(Trimethyltin)isoquinoline; 7-TMS-Isoquinoline
EINECS	Contact for details

Quality Control

Our 7-Trimethylstannylisoquinoline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥95% (by HPLC/NMR). Each lot undergoes comprehensive analysis including identity confirmation (IR, NMR), purity assay, and tests for residual solvents and heavy metals. Certificates of Analysis (COA) are provided with every shipment, detailing all specifications and test results. Our quality management system supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This compound is moisture-sensitive (hygroscopic) and can be easily oxidized; prolonged exposure to air or moisture should be avoided. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Tin (Sn) Content	42.0 - 44.0 %
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.