Description

2H-1-Benzopyran-6-Ol, 7,8-Difluoro-3,4-Dihydro- is a high-purity fluorinated chroman derivative, a key advanced intermediate in modern organic synthesis. This compound is valued for its precise molecular architecture, which enables the construction of complex molecules with specific biological and material properties. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, particularly in therapeutic areas requiring fluorinated scaffolds for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the difluoro-substituted chroman structure can contribute to improved efficacy and environmental profile.
• Material Science: Serves as a precursor for specialty chemicals and functional materials, including liquid crystals and organic electronic components.
• Academic & R&D: Employed in organic chemistry research for method development, catalysis studies, and exploring new reaction pathways involving fluorinated heterocycles.
• Fine Chemical Synthesis: A versatile intermediate for custom synthesis and contract manufacturing of complex, high-value specialty chemicals.

Basic Information

Product Name	2H-1-Benzopyran-6-Ol, 7,8-Difluoro-3,4-Dihydro-
CAS No.	1029476-88-7
Molecular Formula	C9H8F2O2
Molecular Weight	186.16 g/mol
Synonyms	7,8-Difluoro-3,4-dihydro-2H-1-benzopyran-6-ol; 7,8-Difluoro-6-hydroxy-3,4-dihydro-2H-chromene; 6-Hydroxy-7,8-difluorochroman; 7,8-Difluoro-6-hydroxychroman; 7,8-Difluorochroman-6-ol; 1029476-88-7 (CAS); Dihydro-7,8-difluoro-2H-1-benzopyran-6-ol
EINECS	Contact for details

Quality Control

Our 2H-1-Benzopyran-6-Ol, 7,8-Difluoro-3,4-Dihydro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, from early-stage R&D to cGMP-compliant production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.