Description

n-[(1S,2S)-2-Aminocyclohexyl]-N'-[3,5-Bis(Trifluoromethyl)Phenyl]-Thiourea is a high-purity, chiral thiourea derivative designed for advanced chemical synthesis and research. This compound is valued for its role as a sophisticated organocatalyst and a critical building block in the development of novel pharmaceuticals and agrochemicals. It is essential for research institutions and industrial R&D departments focused on asymmetric synthesis, medicinal chemistry, and the creation of high-value specialty chemicals.

Application

• Asymmetric Organocatalysis: Serves as a key chiral catalyst or catalyst precursor for enantioselective organic transformations.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Acts as a building block for novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Investigated for the synthesis of advanced polymers and functional materials with specific chiral properties.
• Chemical Biology Probes: Utilized in the design of molecular probes to study enzyme mechanisms and biological pathways.
• Ligand for Metal Complexes: Functions as a chiral ligand in coordination chemistry for creating asymmetric metal catalysts.

Basic Information

Product Name	n-[(1S,2S)-2-Aminocyclohexyl]-N'-[3,5-Bis(Trifluoromethyl)Phenyl]-Thiourea
CAS No.	1027476-96-5
Molecular Formula	C15H17F6N3S
Molecular Weight	377.37 g/mol
Synonyms	(1S,2S)-N-(3,5-Bis(trifluoromethyl)phenyl)-N'-(2-aminocyclohexyl)thiourea; (1S,2S)-2-Amino-N-(3,5-bis(trifluoromethyl)phenyl)carbamothioylcyclohexan-1-amine; (1S,2S)-1-(3,5-Bis(trifluoromethyl)phenyl)-3-(2-aminocyclohexyl)thiourea; Chiral Thiourea Catalyst; (S,S)-Thiourea Derivative; 1027476-96-5; (1S,2S)-enantiomer of a bis(trifluoromethyl)phenyl thiourea
EINECS	Contact for details

Quality Control

Our production of n-[(1S,2S)-2-Aminocyclohexyl]-N'-[3,5-Bis(Trifluoromethyl)Phenyl]-Thiourea adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral assay, NMR for structural confirmation, and mass spectrometry. A detailed Certificate of Analysis (COA) documenting identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.