Description

8-Bromo-6-Methyl-3,4-Dihydro-2H-1-Benzopyran-4-One is a high-purity, synthetically valuable chromanone derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and plant growth regulators due to its bioactive chromanone core.
• Organic Synthesis Building Block: The bromine and ketone functionalities make it a versatile substrate for cross-coupling reactions (e.g., Suzuki, Heck) and further heterocyclic ring formation.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and organic electronic materials with specific optical properties.
• Academic & Contract Research: Essential for medicinal chemistry programs and methodological studies in universities and contract research organizations (CROs).

Basic Information

Product Name	8-Bromo-6-Methyl-3,4-Dihydro-2H-1-Benzopyran-4-One
CAS No.	1026982-77-3
Molecular Formula	C10H9BrO2
Molecular Weight	241.08 g/mol
Synonyms	8-Bromo-6-methylchroman-4-one; 8-Bromo-6-methyl-4-chromanone; 8-Bromo-6-methyl-2,3-dihydro-4H-chromen-4-one; 8-Bromo-6-methyl-3,4-dihydro-2H-chromen-4-one; 6-Methyl-8-bromochroman-4-one; 4H-1-Benzopyran-4-one, 8-bromo-3,4-dihydro-6-methyl-2H-; 1026982-77-3
EINECS	Contact for details

Quality Control

Our 8-Bromo-6-Methyl-3,4-Dihydro-2H-1-Benzopyran-4-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.