Description

(S)-2-(Isochroman-1-Yl)Ethyl Methanesulfonate is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic utility. Its value lies in its role as a key precursor for the synthesis of complex, biologically active molecules, particularly in the development of new therapeutic agents. This compound is essential for research and production chemists in the pharmaceutical, biotechnology, and fine chemical industries who require enantiomerically pure intermediates for advanced drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of potential drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Asymmetric Synthesis: Used in the construction of complex molecular architectures requiring high enantiomeric purity for structure-activity relationship (SAR) studies.
• Process Chemistry & Scale-Up: Serves as a validated starting material or intermediate for the development and optimization of commercial-scale API (Active Pharmaceutical Ingredient) manufacturing routes.
• Medicinal Chemistry Research: Employed in lead optimization and the discovery of novel bioactive compounds in academic and industrial R&D laboratories.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals and advanced materials where precise stereochemistry is required.

Basic Information

Product Name	(S)-2-(Isochroman-1-Yl)Ethyl Methanesulfonate
CAS No.	1026828-66-9
Molecular Formula	C12H16O4S
Molecular Weight	256.32 g/mol
Synonyms	(S)-1-(2-(Methylsulfonyloxy)ethyl)isochroman; (S)-2-(Isochroman-1-yl)ethyl methanesulfonate; Methanesulfonic acid (S)-2-(isochroman-1-yl)ethyl ester; (S)-Isochroman-1-ylethyl mesylate; (S)-1-(2-Mesyloxyethyl)isochroman; (S)-1,2,3,4-Tetrahydro-1-[[2-[(methylsulfonyl)oxy]ethyl]]-2H-1-benzopyran
EINECS	Contact for details

Quality Control

Our (S)-2-(Isochroman-1-Yl)Ethyl Methanesulfonate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by HPLC), enantiomeric excess, and impurity profiles. We adhere to cGMP principles for pharmaceutical intermediates, ensuring traceability and documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.