Description

2-Fluoro-5-Methyl-3-(Tributylstannyl)Pyridine is a high-value organotin intermediate featuring a functionalized pyridine core. This compound is critical for facilitating efficient Stille cross-coupling reactions, enabling the synthesis of complex molecules with high selectivity. It is primarily sought after by research and development teams in the pharmaceutical and advanced materials sectors for constructing novel active pharmaceutical ingredients (APIs) and functional organic compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for constructing complex heterocyclic systems via palladium-catalyzed cross-coupling.
• Agrochemical Research: Used in the development of new pesticides and herbicides where the pyridine-stannane moiety is incorporated for bioactivity.
• Material Science: Serves as a precursor in the creation of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Synthesis: An essential reagent in academic and industrial laboratories for methodological development in organometallic chemistry and catalysis.
• Ligand Synthesis: Can be utilized to prepare novel pyridine-based ligands for coordination chemistry and catalytic applications.

Basic Information

Product Name	2-Fluoro-5-Methyl-3-(Tributylstannyl)Pyridine
CAS No.	1025745-87-2
Molecular Formula	C18H32FNSn
Molecular Weight	400.16 g/mol
Synonyms	3-Tributylstannyl-2-fluoro-5-methylpyridine; 2-Fluoro-5-methyl-3-(tributylstannyl)pyridine; Tributyl(2-fluoro-5-methyl-3-pyridyl)stannane; 2-Fluoro-5-methylpyridin-3-yltributylstannane; 5-Methyl-2-fluoro-3-(tributylstannyl)pyridine; Pyridine, 2-fluoro-5-methyl-3-(tributylstannyl)-; Stannane, tributyl(2-fluoro-5-methyl-3-pyridinyl)-
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-Methyl-3-(Tributylstannyl)Pyridine is produced and tested under strict quality management protocols to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its moisture-sensitive (hygroscopic) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Tin (Sn) Content	29.0 - 30.5 %
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.