Description

Potassium 3-Trifluoroboratopropionate tert-Butyl Ester is a high-value organoboron reagent, specifically a potassium trifluoroborate salt, prized for its enhanced stability and handling properties compared to traditional boronic acids. This compound serves as a critical building block in modern synthetic chemistry, enabling efficient cross-coupling reactions to construct complex molecular architectures. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate Synthesis: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heteroaryl motifs prevalent in drug candidates.
• Agrochemical Research & Development: Used to create novel active ingredients with specific biological activity for crop protection products.
• Material Science: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Biology & Probe Development: Facilitates the site-specific labeling and modification of biomolecules for diagnostic and research applications.
• Process Chemistry & Scale-up: Its improved stability makes it suitable for optimizing and scaling up synthetic routes in pilot plants and manufacturing.
• Academic & Industrial R&D: A versatile tool for methodological development and exploring new chemical space in organic synthesis laboratories.

Basic Information

Product Name	Potassium 3-Trifluoroboratopropionate tert-Butyl Ester
CAS No.	1023357-66-5
Molecular Formula	C7H11BF3KO2
Molecular Weight	234.07 g/mol
Synonyms	Potassium (3-(tert-Butoxy)-3-oxopropyl)trifluoroboranuide; 3-(tert-Butoxy)-3-oxopropyltrifluoroborate Potassium Salt; tert-Butyl 3-(Trifluoroboranyl)propanoate Potassium Salt; Potassium 3-(tert-Butoxycarbonyl)propyltrifluoroborate; Propanoic acid, 3-(trifluoroboranyl)-, 1,1-dimethylethyl ester, potassium salt (1:1)
EINECS	Contact for details

Quality Control

Our Potassium 3-Trifluoroboratopropionate tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including NMR (1H, 13C, 19F, 11B), HPLC for purity assessment, and KF titration for moisture content, to ensure consistency and reliability for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic (moisture-sensitive) nature. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
11B NMR Purity	≥ 95%
Water Content (KF)	≤ 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.