Description

Potassium 3-Trifluoroboratopropionate Methyl Ester is a specialized organoboron reagent featuring a trifluoroborate (BF3K) group and a methyl ester functionality. This compound is valued for its enhanced stability and solubility compared to traditional boronic acids, making it a crucial building block in modern synthetic chemistry. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for cross-coupling reactions, such as Suzuki-Miyaura couplings, to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science: Serves as a precursor for creating advanced organic electronic materials and liquid crystals.
• Chemical Biology & Proteomics: Employed in the development of bioconjugation tools and activity-based probes.
• Academic & Industrial R&D: A versatile building block for method development and library synthesis in medicinal chemistry.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule construction.

Basic Information

Product Name	Potassium 3-Trifluoroboratopropionate Methyl Ester
CAS No.	1023357-63-2
Molecular Formula	C4H5BF3KO2
Molecular Weight	191.99 g/mol
Synonyms	Potassium (3-Methoxy-3-oxopropyl)trifluoroborate; Methyl 3-(Trifluoroborato)propanoate Potassium Salt; 3-(Trifluoroborato)propionic Acid Methyl Ester Potassium Salt; Potassium 3-(Methoxycarbonyl)propyltrifluoroborate; Methyl 3-(Potassiumtrifluoroborato)propanoate; Potassium Methyl 3-Trifluoroboratopropionate; Propanoic acid, 3-(trifluoroborato)-, methyl ester, potassium salt (1:1)
EINECS	Contact for details

Quality Control

Our Potassium 3-Trifluoroboratopropionate Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay (NMR/HPLC), purity, and moisture content. Our quality system is designed to support cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) when not in use. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (NMR/HPLC)	≥95%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.