Description

4-Phenyl-2-(Tributylstannyl)-Oxazole is a specialized organotin reagent featuring a functionalized oxazole heterocycle. This compound is a valuable building block in advanced organic synthesis, particularly for Stille cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those containing biaryl or heterobiaryl motifs via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and development of new active ingredients for crop protection, leveraging its ability to introduce the phenyl-oxazole moiety.
• Materials Science Research: Serves as a monomer or functional unit in the development of organic electronic materials, such as OLEDs or conductive polymers.
• Methodology Development: Employed in academic and industrial R&D labs to explore new catalytic cycles and synthetic methodologies involving organotin chemistry.
• Ligand and Catalyst Preparation: Acts as a starting material for the synthesis of specialized ligands or organometallic catalysts.
• Chemical Biology Probes: Utilized in the construction of molecular probes for studying biological processes, where the oxazole ring can serve as a bioisostere or fluorescent tag.

Basic Information

Product Name	4-Phenyl-2-(Tributylstannyl)-Oxazole
CAS No.	1019654-81-9
Molecular Formula	C21H33NOSn
Molecular Weight	458.20 g/mol
Synonyms	2-Tributylstannyl-4-phenyloxazole; 4-Phenyl-2-tributylstannyloxazole; Oxazole, 4-phenyl-2-(tributylstannyl)-; Tributyl(4-phenyl-2-oxazolyl)stannane; Stannane, tributyl(4-phenyl-2-oxazolyl)-; (4-Phenyloxazol-2-yl)tributylstannane
EINECS	Contact for details

Quality Control

Every batch of 4-Phenyl-2-(Tributylstannyl)-Oxazole is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing, including NMR (1H, 13C, 119Sn) and HPLC analysis, to ensure high purity and consistency for sensitive synthetic applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (argon or nitrogen) due to its moisture-sensitive and air-sensitive nature. Keep away from heat and open flames. For long-term storage, consider storage at or below -20°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Area %)
Tin (Sn) Content	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.