Description

(S)-6-Methoxychroman-4-Amine is a chiral amine derivative of chroman, serving as a high-value pharmaceutical intermediate and chiral building block. Its enantiopure structure is critical for imparting specific biological activity and selectivity in advanced drug discovery and development. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly within central nervous system (CNS) and cardiovascular research.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a building block in stereoselective synthesis for creating complex molecular architectures.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• CNS Drug Development: Potential precursor in the synthesis of compounds targeting neurological pathways.
• Catalyst and Ligand Synthesis: Can be utilized to develop chiral catalysts or ligands for enantioselective transformations.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development.

Basic Information

Product Name	(S)-6-Methoxychroman-4-Amine
CAS No.	1018978-90-9
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	(4S)-6-Methoxy-3,4-dihydro-2H-1-benzopyran-4-amine; (S)-6-Methoxy-3,4-dihydro-2H-chromen-4-amine; (S)-6-Methoxy-3,4-dihydro-2H-1-benzopyran-4-amine; (S)-4-Amino-6-methoxychroman; 6-Methoxychroman-4-amine, (S)-; (S)-6-Methoxy-3,4-dihydro-2H-chromen-4-ylamine
EINECS	Contact for details

Quality Control

Our (S)-6-Methoxychroman-4-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.