Description

(R)-6-Methoxychroman-4-Amine is a chiral amine derivative of chroman, serving as a high-value pharmaceutical intermediate and building block in organic synthesis. This compound matters for its role in constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) with specific biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in areas requiring enantiomerically pure scaffolds.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of potential drug candidates, especially in central nervous system (CNS) and cardiovascular research.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and for creating focused libraries of bioactive compounds.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in API manufacturing.
• Agrochemical Synthesis: Potential intermediate in the development of chiral agrochemicals with enhanced efficacy and environmental profile.

Basic Information

Product Name	(R)-6-Methoxychroman-4-Amine
CAS No.	1018978-89-6
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	(R)-6-Methoxy-3,4-dihydro-2H-1-benzopyran-4-amine; (4R)-6-Methoxy-3,4-dihydro-2H-chromen-4-amine; (R)-4-Amino-6-methoxychroman; (R)-6-Methoxy-4-chromanamine; (R)-6-Methoxychroman-4-ylamine; 6-Methoxychroman-4-amine, (R)-; (R)-enantiomer of 6-Methoxychroman-4-amine
EINECS	Contact for details

Quality Control

Our (R)-6-Methoxychroman-4-Amine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.