Description

(S)-6-Methylchroman-4-Amine is a chiral amine derivative of chroman, a privileged scaffold in medicinal chemistry. This compound is a valuable building block for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily utilized by pharmaceutical companies and contract research organizations (CROs) engaged in drug discovery programs targeting central nervous system (CNS) disorders, cardiovascular diseases, and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs).
• Drug Discovery Scaffold: Used in high-throughput screening and combinatorial chemistry to create libraries of bioactive compounds.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective chemical reactions.
• Medicinal Chemistry Research: Investigated for its potential biological activity, particularly in modulating serotonin and adrenergic receptors.
• Chemical Biology Probes: Used in the development of molecular probes to study enzyme function and biological pathways.
• Agrochemical Research: Serves as a precursor in the development of novel crop protection agents.

Basic Information

Product Name	(S)-6-Methylchroman-4-Amine
CAS No.	1018978-88-5
Molecular Formula	C10H13NO
Molecular Weight	163.22 g/mol
Synonyms	(4S)-6-Methyl-3,4-dihydro-2H-1-benzopyran-4-amine; (S)-6-Methyl-3,4-dihydro-2H-chromen-4-amine; (S)-6-Methyl-3,4-dihydro-2H-1-benzopyran-4-amine; (S)-6-Methylchroman-4-ylamine; 6-Methylchroman-4-amine, (S)-; (S)-4-Amino-6-methylchroman
EINECS	Contact for details

Quality Control

Our (S)-6-Methylchroman-4-Amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and enantiomeric excess (ee). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality standards are designed to meet the stringent requirements of pharmaceutical R&D and GMP-guided synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.