Description

3-Chloro-4-Ethoxy-5-Fluorocinnamic Acid is a high-purity, multi-functional cinnamic acid derivative designed for advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate, particularly valuable for constructing complex molecules in drug discovery and development. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality building blocks for active ingredient synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially in therapeutic areas requiring complex fluorinated and chlorinated structures.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated aromatic system.
• Liquid Crystal Material Precursor: Serves as a starting material for synthesizing fluorinated liquid crystal compounds used in display technologies.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a core component in the development of electron-transport or emissive layer materials for OLED devices.
• Chemical Research & Development: Employed in academic and industrial R&D for studying structure-activity relationships, cross-coupling reactions, and as a scaffold for library synthesis.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals, dyes, and pigments where specific halogen and ether substitutions are required.

Basic Information

Product Name	3-Chloro-4-Ethoxy-5-Fluorocinnamic Acid
CAS No.	1017779-08-6
Molecular Formula	C₁₁H₁₀ClFO₃
Molecular Weight	244.65 g/mol
Synonyms	(E)-3-(3-Chloro-4-ethoxy-5-fluorophenyl)acrylic acid; 3-Chloro-4-ethoxy-5-fluorocinnamic acid; 2-Propenoic acid, 3-(3-chloro-4-ethoxy-5-fluorophenyl)-, (2E)-; (E)-3-(3-Chloro-4-ethoxy-5-fluorophenyl)-2-propenoic acid; 3-Chloro-4-ethoxy-5-fluorocinnamate; CAEF; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-4-Ethoxy-5-Fluorocinnamic Acid is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.