Description

4-(4-Methoxy-Phenyl)-Tetrahydro-Pyran-4-Ylamine is a versatile chiral amine building block featuring a unique tetrahydro-pyran scaffold. This compound matters for its critical role in the synthesis of complex pharmaceutical intermediates and fine chemicals, enabling the development of novel therapeutic agents. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-purity intermediate for constructing active pharmaceutical ingredients (APIs), particularly in projects requiring specific stereochemistry and molecular complexity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and other therapeutic areas.
• Asymmetric Synthesis: Serves as a valuable building block for constructing complex molecules via asymmetric synthesis routes, leveraging its amine functionality and stereogenic center.
• Ligand and Catalyst Preparation: Used in the preparation of chiral ligands and organocatalysts for enantioselective transformations.
• Agrochemical Research: Employed in the synthesis of novel agrochemicals and plant protection agents requiring specific amine-based architectures.
• Material Science: Potential monomer or precursor for advanced polymers and functional materials with specific chemical properties.

Basic Information

Product Name	4-(4-Methoxy-Phenyl)-Tetrahydro-Pyran-4-Ylamine
CAS No.	1017465-69-8
Molecular Formula	C13H19NO2
Molecular Weight	221.30 g/mol
Synonyms	4-(4-Methoxyphenyl)tetrahydro-2H-pyran-4-amine; 4-Amino-4-(4-methoxyphenyl)tetrahydro-2H-pyran; 4-(p-Methoxyphenyl)tetrahydro-2H-pyran-4-amine; 4-(4-Methoxyphenyl)oxan-4-amine; 4-(4-Methoxyphenyl)tetrahydropyran-4-amine; 4-(4-Methoxy-phenyl)-tetrahydro-pyran-4-ylamine
EINECS	Contact for details

Quality Control

Our 4-(4-Methoxy-Phenyl)-Tetrahydro-Pyran-4-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.