Description

4-(4-Chloro-Phenyl)-Tetrahydro-Pyran-4-Ylamine is a versatile chiral amine building block featuring a tetrahydro-2H-pyran scaffold substituted with a chlorophenyl group. This compound is of significant value in pharmaceutical research and development due to its rigid, three-dimensional structure, which is crucial for creating molecules with specific biological activity and improved metabolic stability. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of central nervous system (CNS) drugs, antiviral agents, and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging its chlorophenyl moiety.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis to produce enantiomerically pure compounds.
• Chemical Biology Probes: Employed in the design of molecular probes for studying enzyme function and receptor interactions.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers with unique thermal or optical properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, functionalized heterocyclic amines.

Basic Information

Product Name	4-(4-Chloro-Phenyl)-Tetrahydro-Pyran-4-Ylamine
CAS No.	1017450-84-8
Molecular Formula	C11H14ClNO
Molecular Weight	211.69 g/mol
Synonyms	4-(4-Chlorophenyl)tetrahydro-2H-pyran-4-amine; 4-Amino-4-(4-chlorophenyl)tetrahydro-2H-pyran; 4-(4-Chlorophenyl)-4-aminotetrahydropyran; 4-(p-Chlorophenyl)-4-aminotetrahydropyran; 4-(4-Chlorophenyl)tetrahydropyran-4-amine; 4-(4-Chloro-phenyl)-tetrahydro-pyran-4-ylamine; 1-(4-Chlorophenyl)-4-aminotetrahydropyran
EINECS	Contact for details

Quality Control

Our 4-(4-Chloro-Phenyl)-Tetrahydro-Pyran-4-Ylamine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.