Description

1-(4-Chlorophenyl)-2,2-Dimethylpropan-1-Amine is a specialized organic amine building block featuring a chlorinated aromatic ring and a sterically hindered neopentyl-like amine structure. This unique molecular architecture makes it a valuable intermediate for the synthesis of advanced pharmaceutical compounds and agrochemicals, where it can impart specific biological activity and metabolic stability. It is primarily sought by research and development chemists and process scale-up teams in the fine chemical, pharmaceutical, and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, anti-infectives, or other therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, or insecticides, where the chlorophenyl and hindered amine groups can contribute to pesticidal activity and environmental persistence profiles.
• Ligand and Catalyst Preparation: Used in the preparation of specialized ligands for asymmetric catalysis or as a precursor for metal-organic frameworks (MOFs) and other advanced materials.
• Organic Synthesis Research: Employed in academic and industrial R&D for constructing complex molecules, studying reaction mechanisms, or developing new synthetic methodologies involving sterically hindered amines.
• Fine Chemical Production: An intermediate in the multi-step synthesis of dyes, pigments, or other performance chemicals requiring a specific aromatic amine backbone.

Basic Information

Product Name	1-(4-Chlorophenyl)-2,2-Dimethylpropan-1-Amine
CAS No.	1016760-61-4
Molecular Formula	C11H16ClN
Molecular Weight	197.70 g/mol
Synonyms	1-(4-Chlorophenyl)-2,2-dimethylpropan-1-amine; 4-Chloro-α,α-dimethylbenzenemethanamine; p-Chloro-α,α-dimethylbenzylamine; 1-Amino-2,2-dimethyl-1-(4-chlorophenyl)propane; (4-Chlorophenyl)(1,1-dimethylethyl)methanamine; 1-(p-Chlorophenyl)-2,2-dimethylpropylamine; Benzenemethanamine, 4-chloro-α,α-dimethyl-
EINECS	Contact for details

Quality Control

Our production of 1-(4-Chlorophenyl)-2,2-Dimethylpropan-1-Amine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment. We support development and commercial projects requiring compliance with cGMP, ISO, or other regulatory frameworks upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.