Description

Potassium 3-(2-Hydroxyethyl)Phenyltrifluoroborate is a versatile organotrifluoroborate salt, a crucial class of reagents prized for their stability and reactivity in modern synthetic chemistry. This compound serves as a key building block for the Suzuki-Miyaura cross-coupling reaction, enabling the efficient formation of carbon-carbon bonds to construct complex molecular architectures. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides by constructing biaryl and functionalized aromatic structures.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Material Science Research: Acts as a monomer or building block for creating organic electronic materials, such as polymers for OLEDs and conductive films.
• Chemical Biology Probes: Utilized in the labeling and modification of biomolecules for diagnostic and research applications.
• Fine Chemical Production: Integral to the scalable manufacturing of complex, high-value aromatic compounds for various industrial applications.

Basic Information

Product Name	Potassium 3-(2-Hydroxyethyl)Phenyltrifluoroborate
CAS No.	1015082-80-0
Molecular Formula	C8H9BF3KO
Molecular Weight	228.06 g/mol
Synonyms	Potassium (3-(2-Hydroxyethyl)phenyl)trifluoroborate; [3-(2-Hydroxyethyl)phenyl]trifluoroboronic Acid Potassium Salt; 2-(3-Trifluoroboratomethylphenyl)ethanol Potassium Salt; Potassium 3-(2-Hydroxyethyl)benzenetrifluoroborate; (3-(2-Hydroxyethyl)phenyl)Potassium Trifluoroborate; Borate(1-), [3-(2-hydroxyethyl)phenyl]trifluoro-, potassium (1:1); Potassium Trifluoro[3-(2-hydroxyethyl)phenyl]borate
EINECS	Contact for details

Quality Control

Our Potassium 3-(2-Hydroxyethyl)Phenyltrifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 19F, 11B), HPLC for purity, and KF titration for moisture content, to ensure it meets the high standards required for sensitive cross-coupling reactions. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) to prevent degradation. Keep away from strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
NMR Purity (1H)	≥ 95.0%
Solubility Test	Soluble in common polar aprotic solvents (e.g., DMF, DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.