Description

Potassium 4-(Hydroxymethyl)Phenyltrifluoroborate is an organotrifluoroborate salt, a highly valuable and stable boronic acid derivative used extensively in modern synthetic chemistry. Its primary value lies in its exceptional stability and handling properties compared to traditional boronic acids, enabling more robust and reliable cross-coupling reactions. This reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for Suzuki-Miyaura couplings and other transition metal-catalyzed transformations.

Application

• Pharmaceutical Intermediate Synthesis: A key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Development: Used in the research and production of novel herbicides, fungicides, and insecticides that require the introduction of a hydroxymethylphenyl moiety.
• Liquid Crystal & OLED Material Production: Serves as a precursor in the manufacture of advanced organic electronic materials for displays and lighting.
• Polymer & Functional Material Chemistry: Enables the incorporation of functional aromatic groups into polymers and specialty materials to modify their properties.
• Chemical Biology & Bioconjugation: Utilized in the labeling and modification of biomolecules due to the reactivity of the boronate group and the handle provided by the hydroxymethyl group.
• Academic & Industrial R&D: A staple reagent in laboratory-scale research for method development and exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Product Name	Potassium 4-(Hydroxymethyl)Phenyltrifluoroborate
CAS No.	1015082-78-6
Molecular Formula	C7H7BF3KO
Molecular Weight	214.04 g/mol
Synonyms	Potassium (4-(Hydroxymethyl)phenyl)trifluoroborate; 4-(Hydroxymethyl)phenyltrifluoroborate Potassium Salt; Potassium 4-(Hydroxymethyl)benzenetrifluoroborate; (4-(Hydroxymethyl)phenyl)trifluoroboronic Acid Potassium Salt; 4-(Hydroxymethyl)benzeneboronic Acid Trifluoroborate Potassium Complex; Potassium Trifluoro(4-(hydroxymethyl)phenyl)borate; p-(Hydroxymethyl)phenyltrifluoroborate Potassium Salt
EINECS	Contact for details

Quality Control

Our Potassium 4-(Hydroxymethyl)Phenyltrifluoroborate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. Each lot undergoes comprehensive analytical testing, including NMR, HPLC, and elemental analysis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and reactivity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.