Description

Potassium 4-Hydroxyphenyltrifluoroborate is an organoboron reagent widely used in modern synthetic chemistry. This compound matters as a key building block in Suzuki-Miyaura cross-coupling reactions, enabling the efficient formation of carbon-carbon bonds to create complex biaryl structures. It is primarily needed by pharmaceutical, agrochemical, and advanced materials research and development teams for constructing active pharmaceutical ingredients (APIs), novel chemical entities, and functional organic molecules.

Application

• Pharmaceutical Intermediate Synthesis: A crucial reagent for constructing biaryl and heterobiaryl scaffolds found in numerous drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages for bioactivity.
• Material Science Research: Serves as a precursor for creating organic electronic materials, liquid crystals, and polymers with tailored optical or electronic properties.
• Catalysis & Ligand Development: Employed in the preparation of specialized ligands and catalysts for asymmetric synthesis and other transition metal-catalyzed processes.
• Chemical Biology & Probe Synthesis: Utilized to label biomolecules or create chemical probes for studying biological pathways and target engagement.
• Academic & Contract Research: A staple reagent in university and CRO laboratories for methodological development and the synthesis of novel organic compounds.

Basic Information

Product Name	Potassium 4-Hydroxyphenyltrifluoroborate
CAS No.	1015082-71-9
Molecular Formula	C6H5BF3KO
Molecular Weight	188.01 g/mol
Synonyms	Potassium (4-Hydroxyphenyl)trifluoroborate; 4-Hydroxyphenyltrifluoroborate Potassium Salt; Potassium 4-Hydroxybenzenetrifluoroborate; (4-Hydroxyphenyl)trifluoroboronic Acid Potassium Salt; 4-Hydroxybenzeneboronic Acid Trifluoroborate Potassium Complex; p-Hydroxyphenyltrifluoroborate Potassium; Potassium p-Hydroxyphenyltrifluoroborate; B-(4-Hydroxyphenyl)trifluoroborate Potassium
EINECS	Contact for details

Quality Control

Our Potassium 4-Hydroxyphenyltrifluoroborate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as assay, NMR purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) in a desiccator for long-term stability. Recommended storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (NMR)	Conforms to structure
Purity (NMR)	≥ 95%
Assay (Potentiometric Titration)	≥ 97%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.