Description

1-(Pyridin-3-Yl)-1H-Pyrazole-4-Carboxylic Acid is a heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific pyrazole-pyridine motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides that leverage its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for chelating ligands in coordination chemistry and catalysis due to its nitrogen-rich structure and carboxylic acid functionality.
• Material Science Research: Employed in the synthesis of organic semiconductors, metal-organic frameworks (MOFs), and other functional materials.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and tools to study biological systems.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	1-(Pyridin-3-Yl)-1H-Pyrazole-4-Carboxylic Acid
CAS No.	1014631-89-0
Molecular Formula	C9H7N3O2
Molecular Weight	189.17 g/mol
Synonyms	3-(1H-Pyrazol-1-yl)pyridine-4-carboxylic acid; 1-(3-Pyridyl)-1H-pyrazole-4-carboxylic acid; 1H-Pyrazole-4-carboxylic acid, 1-(3-pyridinyl)-; 1-(Pyridin-3-yl)-1H-pyrazole-4-carboxylic acid; Pyrazole-4-carboxylic acid, 1-(3-pyridyl)-; 1014631-89-0; 1-(3-Pyridinyl)-1H-pyrazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(Pyridin-3-Yl)-1H-Pyrazole-4-Carboxylic Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.