Description

Potassium 2-Fluoro-5-Formylphenyltrifluoroborate is a versatile organotrifluoroborate salt, a crucial class of reagents prized for their stability and reactivity in cross-coupling reactions. This compound is specifically engineered to serve as a key synthetic intermediate, enabling the efficient and selective introduction of a formyl-substituted fluorophenyl moiety into complex molecular architectures. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for Suzuki-Miyaura coupling and other metal-catalyzed transformations.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic systems and aldehyde functional handles for further derivatization.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the fluorine atom and formyl group impart desired biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and other advanced catalytic processes.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and organic electronic materials where precise control over molecular structure is required.
• Suzuki-Miyaura Cross-Coupling: Functions as a stable, air- and moisture-tolerant boronic acid equivalent for palladium-catalyzed carbon-carbon bond formation, offering advantages over traditional boronic acids.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for imaging and diagnostic applications due to its reactive aldehyde group for bioconjugation.

Basic Information

Item	Details
Product Name	Potassium 2-Fluoro-5-Formylphenyltrifluoroborate
CAS No.	1012868-70-0
Molecular Formula	C7H4BF4KO2
Molecular Weight	245.92 g/mol
Synonyms	Potassium (2-Fluoro-5-formylphenyl)trifluoroborate; 2-Fluoro-5-formylbenzenetrifluoroborate Potassium Salt; Potassium 2-Fluoro-5-formylbenzenetrifluoroboronate; (2-Fluoro-5-formylphenyl)trifluoroboronic Acid Potassium Salt; 5-Formyl-2-fluorophenyltrifluoroborate Potassium Salt; Potassium Trifluoro(2-fluoro-5-formylphenyl)borate; Potassium (5-Formyl-2-fluorophenyl)trifluoroborate; 2-Fluoro-5-formylphenyl-BF3K
EINECS	Contact for details

Quality Control

Our Potassium 2-Fluoro-5-Formylphenyltrifluoroborate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable. Each lot is comprehensively analyzed using advanced techniques including NMR (1H, 13C, 19F, 11B), HPLC, and KF titration to confirm identity, purity, and moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) for prolonged storage or after opening to prevent degradation. Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0 %
NMR Purity (19F)	≥ 97%
Solubility	Soluble in common polar organic solvents (e.g., DMF, DMSO, MeOH)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.