Description

1H-Imidazole, 2-(4-Bromophenyl)-5-(Trifluoromethyl)- is a high-value, multi-functional heterocyclic building block distinguished by its bromophenyl and trifluoromethyl substituents. This compound is engineered to serve as a critical intermediate in advanced organic synthesis, offering unique reactivity for constructing complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antiviral agent discovery.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, leveraging the bioactivity of the imidazole core and halogenated aryl groups.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Catalyst Ligand Development: The imidazole structure can be modified to create novel ligands for transition metal catalysis in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: An essential building block for custom synthesis services catering to the fine chemical and life science industries.

Basic Information

Product Name	1H-Imidazole, 2-(4-Bromophenyl)-5-(Trifluoromethyl)-
CAS No.	1010837-60-1
Molecular Formula	C10H6BrF3N2
Molecular Weight	291.07 g/mol
Synonyms	2-(4-Bromophenyl)-5-(trifluoromethyl)-1H-imidazole; 2-(4-Bromophenyl)-5-(trifluoromethyl)imidazole; 5-(Trifluoromethyl)-2-(4-bromophenyl)imidazole; 1H-Imidazole, 2-(4-bromophenyl)-5-(trifluoromethyl)-; 4-Bromo-α,α,α-trifluoro-2-imidazol-2-yltoluene
EINECS	Contact for details

Quality Control

Our production of 1H-Imidazole, 2-(4-Bromophenyl)-5-(Trifluoromethyl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). This compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.