Description

4-(Hydroxymethyl)Tetrahydro-2H-Pyran-4-Carbonitrile is a versatile bifunctional chemical intermediate featuring both a hydroxymethyl group and a nitrile moiety on a tetrahydropyran scaffold. This unique structure makes it a valuable building block for the synthesis of complex molecules in advanced pharmaceutical and agrochemical research. It is particularly sought after by R&D chemists and process development scientists working on novel active ingredients, chiral ligands, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Chiral Ligand & Catalyst Development: The tetrahydropyran ring serves as a scaffold for creating stereoselective catalysts and ligands used in asymmetric synthesis.
• Functional Material Precursor: Used in the research and development of specialty polymers, resins, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a linker or spacer molecule in the design of biochemical probes and bioconjugation reagents.
• Fine Chemical Synthesis: Intermediate for producing complex flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	4-(Hydroxymethyl)Tetrahydro-2H-Pyran-4-Carbonitrile
CAS No.	1010836-56-2
Molecular Formula	C7H11NO2
Molecular Weight	141.17 g/mol
Synonyms	4-(Hydroxymethyl)tetrahydro-2H-pyran-4-carbonitrile; 4-Cyano-4-(hydroxymethyl)tetrahydropyran; Tetrahydro-2H-pyran-4-carbonitrile, 4-(hydroxymethyl)-; 4-Hydroxymethyl-tetrahydropyran-4-carbonitrile; THP-CN-CH2OH; 4-(Hydroxymethyl)-4-cyanotetrahydropyran
EINECS	Contact for details

Quality Control

Our 4-(Hydroxymethyl)Tetrahydro-2H-Pyran-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.