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4-Bromo-2-(Trimethylstannyl)-Pyridine CAS NO 1008750-09-1


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CAS No.:1008750-09-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Bromo-2-(Trimethylstannyl)-Pyridine is a high-value organotin intermediate featuring a reactive bromine substituent and a trimethylstannyl group on a pyridine ring. This unique bifunctional structure makes it a critical building block for constructing complex molecules via cross-coupling reactions, such as Stille coupling. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and functional organic compounds.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
  • Organic Synthesis Building Block: Used in Stille coupling reactions to introduce the 2-pyridyl moiety into larger molecular architectures for medicinal chemistry and material science research.
  • Ligand Synthesis: Serves as a starting material for the preparation of specialized nitrogen-containing ligands used in catalysis.
  • Advanced Materials Research: Employed in the development of organic electronic materials, such as those for OLEDs or conductive polymers, where the pyridine unit is integral.
  • Agrochemical Intermediate: Utilized in the research and development of novel crop protection agents and herbicides.
  • Chemical Biology Probes: Acts as a synthetic handle for creating labeled compounds or probes for biological target identification and study.

Basic Information

Item Detail
Product Name 4-Bromo-2-(Trimethylstannyl)-Pyridine
CAS No. 1008750-09-1
Molecular Formula C8H12BrNSn
Molecular Weight 328.79 g/mol
Synonyms 2-Trimethylstannyl-4-bromopyridine; 4-Bromo-2-(trimethylstannyl)pyridine; 4-Bromo-2-trimethylstannylpyridine; (4-Bromopyridin-2-yl)trimethylstannane; Pyridine, 4-bromo-2-(trimethylstannyl)-; Trimethyl(4-bromo-2-pyridinyl)stannane
EINECS Contact for details

Quality Control

Every batch of 4-Bromo-2-(Trimethylstannyl)-Pyridine is manufactured and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This compound is hygroscopic (moisture-sensitive) and easily oxidized; therefore, containers must be kept sealed and handled under anhydrous conditions to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Tin (Sn) Content Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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