Description

3,4-Dihydro-2H-Benzo[1,4]Oxazine-8-Carboxylic Acid is a high-value heterocyclic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique benzo-fused oxazine scaffold makes it a versatile intermediate for constructing complex molecular architectures with potential biological activity. This compound is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the development of new active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used as a core scaffold for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers, dyes, and advanced organic materials.
• Academic & Contract Research: Essential reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.
• Chemical Biology: Employed in the design and synthesis of molecular probes and biochemical tools for target identification and validation.

Basic Information

Product Name	3,4-Dihydro-2H-Benzo[1,4]Oxazine-8-Carboxylic Acid
CAS No.	1007875-95-7
Molecular Formula	C9H9NO3
Molecular Weight	179.17 g/mol
Synonyms	8-Carboxy-3,4-dihydro-2H-1,4-benzoxazine; 2H-1,4-Benzoxazine-8-carboxylic acid, 3,4-dihydro-; 3,4-Dihydro-2H-1,4-benzoxazine-8-carboxylic acid; Benzo[1,4]oxazine-8-carboxylic acid, 3,4-dihydro-2H-; 1,4-Benzoxazine-8-carboxylic acid, 3,4-dihydro-2H-; 8-Carboxy-2H-1,4-benzoxazine, 3,4-dihydro-
EINECS	Contact for details

Quality Control

Our 3,4-Dihydro-2H-Benzo[1,4]Oxazine-8-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.