Description

4-(1H-1,2,4-Triazol-1-Yl)-1-[4-(Trifluoromethoxy)Phenyl]-1H-Pyrazol-5-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical manufacturers and contract research organizations (CROs) engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates targeting various disease pathways.
• Agrochemical Research: Used in the development of new fungicides and pesticides, leveraging the bioactivity of the triazole and pyrazole moieties.
• Medicinal Chemistry R&D: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Chemical Biology: Employed as a probe or tool compound in biochemical assays to study enzyme inhibition or receptor binding.
• Custom Synthesis: Starting material for the contract manufacturing of specialized fine chemicals and proprietary molecules.

Basic Information

Product Name	4-(1H-1,2,4-Triazol-1-Yl)-1-[4-(Trifluoromethoxy)Phenyl]-1H-Pyrazol-5-Ol
CAS No.	1007029-49-3
Molecular Formula	C12H8F3N5O2
Molecular Weight	311.22 g/mol
Synonyms	1-[4-(Trifluoromethoxy)phenyl]-4-(1H-1,2,4-triazol-1-yl)-1H-pyrazol-5-ol; 4-(1,2,4-Triazol-1-yl)-1-[4-(trifluoromethoxy)phenyl]-1H-pyrazol-5-ol; 5-Hydroxy-1-[4-(trifluoromethoxy)phenyl]-4-(1H-1,2,4-triazol-1-yl)-1H-pyrazole; 1007029-49-3
EINECS	Contact for details

Quality Control

Our production of 4-(1H-1,2,4-Triazol-1-Yl)-1-[4-(Trifluoromethoxy)Phenyl]-1H-Pyrazol-5-Ol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are manufactured and tested in facilities that follow cGMP (current Good Manufacturing Practice) guidelines where applicable. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.