Description

Hexamethylguanidinium Trifluoromethanolate is a highly reactive, non-nucleophilic superbase. This compound is valued for its exceptional deprotonation power and thermal stability, making it a superior catalyst and reagent in demanding organic transformations. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for applications requiring strong, non-coordinating bases under anhydrous conditions.

Application

• Catalyst in Organic Synthesis: Employed as a powerful, non-nucleophilic base for deprotonation reactions, including the generation of enolates and other carbanions.
• Pharmaceutical Intermediate Manufacturing: Facilitates key synthetic steps, such as condensations and eliminations, in the production of active pharmaceutical ingredients (APIs).
• Polymerization Initiator: Used in the synthesis of specialized polymers and advanced materials where controlled anionic polymerization is required.
• Agrochemical Synthesis: Acts as a crucial reagent in the preparation of complex herbicide and pesticide molecules.
• Research & Development: A valuable tool in academic and industrial R&D labs for exploring new reaction pathways and methodologies.
• Electrolyte Additive: Investigated for use in high-performance battery systems due to its ionic nature and stability.

Basic Information

Product Name	Hexamethylguanidinium Trifluoromethanolate
CAS No.	1006904-67-1
Molecular Formula	C8H18F3N3O
Molecular Weight	229.25 g/mol
Synonyms	1,1,3,3,3-Hexamethylguanidinium Trifluoromethanesulfonate; HMG-TFMS; Hexamethylguanidinium Triflate; 1,1,3,3,3-Hexamethylguanidinium Trifluoromethanesulphonate; Hünig's Base Triflate Salt; N,N,N',N',N'',N''-Hexamethylguanidinium Trifluoromethanesulfonate; HMGT; Superbase Salt
EINECS	Contact for details

Quality Control

Our Hexamethylguanidinium Trifluoromethanolate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed to confirm identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing specifications such as assay, moisture content (KF), and related substances are provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.