Description

3-[3-(Trifluoromethyl)-1H-Pyrazol-1-Yl]Butanethioamide is a high-value, fluorinated pyrazole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the unique reactivity of the thioamide group combined with the stability and lipophilicity imparted by the trifluoromethylpyrazole moiety, enabling the construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients, particularly in medicinal chemistry for drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in the development of kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl and pyrazole groups.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced materials with specific chemical resistances.
• Ligand Synthesis: Utilized in organometallic chemistry for the preparation of novel chelating ligands used in catalysis and sensor technology.
• Chemical Biology Probe Development: Acts as a core structure for creating molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	3-[3-(Trifluoromethyl)-1H-Pyrazol-1-Yl]Butanethioamide
CAS No.	1006348-58-8
Molecular Formula	C8H10F3N3S
Molecular Weight	237.25 g/mol
Synonyms	1-Butanethioamide, 3-[3-(trifluoromethyl)-1H-pyrazol-1-yl]-; 3-(3-(Trifluoromethyl)-1H-pyrazol-1-yl)butanethioamide; 3-[3-(Trifluoromethyl)pyrazol-1-yl]butanethioamide; 3-(3-Trifluoromethyl-1H-pyrazol-1-yl)butanethioamide; Butanethioamide, 3-[3-(trifluoromethyl)-1H-pyrazol-1-yl]-; CAS 1006348-58-8
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards for research and development. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to verify identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.