Description

Ethyl 6-Chloroimidazo[1,2-B]Pyridazin-2-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities (NCEs).
• Oncology Drug Development: Serves as a core scaffold for developing potential kinase inhibitors and other targeted cancer therapies.
• CNS-Active Compound Synthesis: Employed in the research and development of potential treatments for neurological disorders.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects and scale-up activities.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and pharmacological studies.

Basic Information

Product Name	Ethyl 6-Chloroimidazo[1,2-B]Pyridazin-2-Ylcarbamate
CAS No.	1005785-65-8
Molecular Formula	C9H9ClN4O2
Molecular Weight	240.65 g/mol
Synonyms	Ethyl 6-chloroimidazo[1,2-b]pyridazine-2-carboxylate; 6-Chloroimidazo[1,2-b]pyridazine-2-carboxylic acid ethyl ester; Ethyl 6-chloro-2-imidazo[1,2-b]pyridazinecarboxylate; 1005785-65-8; UNII-9G1K7V7276; 9G1K7V7276; AKOS025147213; SCHEMBL15406227; DB15427
EINECS	Contact for details

Quality Control

Our Ethyl 6-Chloroimidazo[1,2-B]Pyridazin-2-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive (store away from light) and hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.